Is diabetes a disease?
Diabetes mellitus is a group of diseases that are characterized by abnormally high blood glucose levels, resulting from defects in insulin secretion, insulin action, or both. Mechanistically, type 1 diabetes (T1D) results from immune-mediated, pancreatic β-cell destruction and type 2 diabetes (T2D) is generally multifactorial, resulting from increasing insulin resistance, diminishing insulin production (relative or absolute), and impairments in glucose metabolism. While type 2 diabetes is strongly correlated with obesity, not all patients with type 2 diabetes are overweight.
Signs and symptoms of type 1 and type 2 diabetes can include increased thirst and urination, increased appetite, loss of weight, fatigue, change in vision, frequent infection, and patches of darkened skin.