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Interfering Substances and Risks

The following substances are known to interfere with the Dexcom sensor:

SubstanceDescriptionDexcom CGM System(s)RiskSafety Recommendation
Acetaminophen/ParacetamolMedication used to treat pain and feverG4 PLATINUMTaking medications with acetaminophen (such as Tylenol) while wearing the sensor falsely raise your sensor glucose readings. The level of inaccuracy depends on the amount of acetaminophen active in your body and may be different for each person.Acetaminophen is contraindicated with G4 PLATINUM CGM system. Use alternative glucose monitoring approaches.
G5 MobileAcetaminophen is contraindicated with G4 PLATINUM CGM system. Use alternative glucose monitoring approaches.Acetaminophen is contraindicated with G5 Mobile CGM system. Do not rely on CGM data produced by G5 Mobile if you have recently taken acetaminophen.
G6, G6 Glucose Program, G6 ProTaking higher than the maximum dose of acetaminophen (e.g. > 1 gram every 6 hours in adults) may affect sensor readings and make them look higher than they really are.You can take a standard or maximum acetaminophen dose of 1 gram (1,000 mg) every 6 hours and still use sensor readings to make treatment decisions.
HydroxyureaMedication used in the treatment of diseases including cancer and sickle cell anemia.G4 PLATINUMIf you are taking hydroxyurea, your sensor glucose readings will be higher than your actual glucose, which could result in missed hypoglycemia alerts. The level of inaccuracy depends on the amount of hydroxyurea in your body.Talk to your physician about alternative glucose monitoring approaches.
G5 Mobile, G6If you are taking hydroxyurea, your sensor glucose readings will be higher than your actual glucose, which could result in missed hypoglycemia alerts or errors in diabetes management, such as giving yourself a higher dose of insulin due to falsely high sensor glucose values. The level of inaccuracy depends on the amount of hydroxyurea in your body.Do not use your Dexcom CGM System for diabetes treatment decisions if you are taking hydroxyurea. Talk to your physician about alternative glucose monitoring approaches.
G6 Glucose ProgramIf you are taking hydroxyurea, your sensor glucose readings will be higher than your actual glucose, which could result in errors in diabetes management. The level of inaccuracy depends on the amount of hydroxyurea in your body.Do not use your Dexcom CGM System for diabetes treatment decisions if you are taking hydroxyurea. Talk to your physician about alternative glucose monitoring approaches.
G6 ProThe use of hydroxyurea will result in sensor glucose readings that are higher than actual glucose levels. The level of inaccuracy in sensor glucose readings is based on the amount of hydroxyurea in the body. Relying on sensor glucose results while taking hydroxyurea could result in missed hypoglycemia alerts or errors in diabetes management, such as giving a higher dose of insulin than necessary to correct falsely high sensor glucose values. It can also result in errors when reviewing, analyzing and interpreting historical patterns for assessing glucose control.Do not use the Dexcom CGM System for making diabetes treatment decisions or assessing glucose control when taking hydroxyurea.